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The Origin of Life - Theories
Feb 19 2010, 6:32 pm
By: RetPallylol
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Feb 23 2010, 5:37 pm CecilSunkure Post #21



No I do not, I get most of my information pertaining to these sorts of topics from my IB Biology class. I've never heard of that website.

As for the irreducibility of cells, I never thought anyone would want to debate that. The thing is, there are plenty of things we do not know about cells, especially pertaining to DNA replication. One example of this would be the long segments of code in the genetic material that are extremely repetitive and seem to serve no purpose, as they aren't actually translated into the RNA strands to be used in transcription. These segments, if I recall correctly, look something like AAACCAAACCAAACC and so on; very repetitive and seemingly useless. I'm sure the function of certain aspects of cells are vague or unknown, or that certain aspects of certain cells aren't necessary in certain circumstances.

I should clarify: the macro processes of cells are all necessary, in present circumstances, for cells to survive. Cells need their nucleus, they need their bi-lipid layers to have both a hydrophobic tail and hydrophylic head, they need ribsomes in order to synthesize proteins, etc. etc.

The point wasn't that cells are perfectly irreducibly complex, but that the complexity necessary to have functioning and living material is a very complex starting point.

Post has been edited 1 time(s), last time on Feb 24 2010, 2:39 am by Cervantes.



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Feb 23 2010, 11:33 pm ProtoTank Post #22



Quote
Cells need their nucleus
no they don't.
Quote
Prokaryotic cells do not have a nucleus, their genetic material is free in the cytoplasm as they do not have a need for compartmentalisation like more complex Eukaryotic cells that carry out more internal chemical mechanisms.

Some Eukaryotic cells do not have a nucleus though, for example a red blood cell ejects its nucleus when mature as it no longer has a need for it and it needs as much room as possible for storing oxygen.




I'm only here because they patched SC1 and made it free.

Feb 24 2010, 1:15 am BeDazed Post #23



Prokaryotic cells require genetic material, means of energy production, means of surviving in a hostile environment, and means of reproduction.
In another case, RBCs do not reproduce. They are produced by bone marrow cells with a nucleus, which is the genetic material necessary to create RBCs.
So. Whats your point?

I might as well as put my two cents here.
What I was trying to say is that, there are just so many possibilities that are just 'possible'. But we will never know the 'truth' behind life. I do not think life could have been formed in a single method- there would be multiple methods that made life possible. And unless we traveled back in time to find out what really happened, nobody can reach a conclusion. No, it is illogical to reach a conclusion until then.



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Feb 24 2010, 6:49 pm ClansAreForGays Post #24



Quote
I might as well as put my two cents here.
What I was trying to say is that, there are just so many possibilities that are just 'possible'. But we will never know the 'truth' behind life. I do not think life could have been formed in a single method- there would be multiple methods that made life possible. And unless we traveled back in time to find out what really happened, nobody can reach a conclusion. No, it is illogical to reach a conclusion until then.
I like how you're talking like anyone ever said we have come to a conclusion, or that it is necessary that we do.
And if you're gonna back with "I never said you said that" then why bring it up int he first place for no reason? I don't go into SC2 topic just to say "well we don't know for sure anything about what sc2 will be lie on launch" just to try and sound smart.




Feb 24 2010, 10:23 pm BeDazed Post #25



If one makes up his mind, then that's their equivalent to a conclusion. I can bring whatever I 'view' here. If you're not refuting my 'view', then it supports the fact that this topic will just be a long list of theories.



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Feb 25 2010, 8:14 pm RIVE Post #26

Just Here For The Pie

I hate delving for information to be used in a serious discussion, but one of my friends on YouTube had just recently submitted this video about a theory of the origin of life.


Most of what has already been stated from this topic can be found in the video.



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Mar 4 2010, 6:02 pm Rantent Post #27



In my opinion, life did not completely originate here. However, it is probable that many compounds were delivered on meteors. This is because space is generally a harsher environment, and can produce compounds that we would normally never see anywhere else. These could then come to earth and interact with the chemicals we have already here and create life. The meteors did not deliver cells though.

Also I believe that life at it's origin was not at all like what we generally think of as simple organisms. They were probably large bodiless enzymatic liquids. (Some quasi-organelles with no coherence.) Unfortunately, due to evolution and competition, these organisms would have been the first to be eaten/destroyed/outdone by things with cell walls. Things always get smaller and more efficient as time goes on.



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Mar 5 2010, 5:33 am grAffe Post #28



Quote from Rantent
In my opinion, life did not completely originate here. However, it is probable that many compounds were delivered on meteors. This is because space is generally a harsher environment, and can produce compounds that we would normally never see anywhere else. These could then come to earth and interact with the chemicals we have already here and create life. The meteors did not deliver cells though.

Also I believe that life at it's origin was not at all like what we generally think of as simple organisms. They were probably large bodiless enzymatic liquids. (Some quasi-organelles with no coherence.) Unfortunately, due to evolution and competition, these organisms would have been the first to be eaten/destroyed/outdone by things with cell walls. Things always get smaller and more efficient as time goes on.
The problem is that in the Christian religion, according to the Bible and its creation story, when sin entered the world, life went from perfect to the state it is today. Basically, organisms went from perfectly efficient to the less efficient state we were in today. In my opinion, this view of the static universe that the Christians preach is mainly due to humans' egocentrism. The world is bound to what they can see at that moment. "macro"evolution is simply another word for "changes that man cannot see within his lifetime." And since we cannot observe these changes, these changes cannot occur, according to creationists.

What they don't realize is that the idea of animal species itself is an arbitrary and qualitative observation made by man. I recently came up with an analogy to demonstrate my idea of different species on this planet (I'm sorry if it's not very good). Let's compare all of life to a color spectrum, ranging from red to violet, with the colors slowly transitioning from one to another. We can make a qualitative distinction between red and orange, just as we can see the difference between a fellow human being and a chimpanzee. What I compare evolution to is the gradual shift from one end to the other of the color spectrum. The difference between you and your offspring is deemed as insignificant because the color equivalent would be perhaps an extremely small increment in the spectrum. However, there is a change, nonetheless. Maybe within our lifetime, we will only see a shift from red to red with a hint of orange, or even less than that. However, the significance lies not in "how much change" but the presence of change itself. The fact that we see "micro"evolution take place shows us that the velocity of movement within the color spectrum is not zero. And any non-zero change in color will eventually lead to violet. I know this isn't the best example to use for evolution (since it's not a straight line, but more like a branching tree), but I think my example better demonstrates the idea of change. Sorry for the terrible analogy, but I hope you get my point (somewhat).



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Mar 6 2010, 6:06 am rayNimagi Post #29



How can raw energy ALWAYS be destructive? Some chemicals/compounds need energy to be created (think endothermic reactions). And how do you qualify "raw" energy? Light seems to be "raw" energy, I guess it can't be used to create glucose through photosynthesis.

The most probable theory of abiogenesis is that a few relatively simple chemicals found a way to reproduce themselves. Unhindered, they multiplied until some mutated, much like any other organism. Over millions or billions of years they became more complex, until mitochondria and chloroplasts formed. They then evolved other organelles, cell walls, "modern" DNA, et cetera. The likelihood of finding suitable combinations increased after billions of years due to the sheer number of "dice rolls."



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Mar 6 2010, 4:27 pm CecilSunkure Post #30



Most raw energy applied without intelligent intervention is destructive. The sun gives you sunburn, and pales color over time. I didn't say everytime there is an exchange of energy, I just said most of the time. Taking this into account in a time before chlorophyll makes it seem unlikely that anything constructive and relevant would happen from sudden jolts of lighting or the like during abiogenesis. I still don't see how tagging on the "It happened for millions of years" prefix makes things seem more likely to happen; adding on years just adds on time for entropic affects to take place upon the system, the system being these chemical reactions brining forth life. Your "dice" cannot last for millions of years at a time can they? I think that a chemical system in an untamed world wouldn't ever last nearly this long due to natural occurrences on the earth. Sure, if you had some sort of invincible dice that could roll for millions of years, they might then land on their side.



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Mar 6 2010, 8:40 pm Rantent Post #31



Explain destructive. Certainly energy is not destructive to life. Things tend not to survive well near absolute zero.
Energy mixes things up, which is good, so long as they aren't too shaken.



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Mar 8 2010, 1:30 am CecilSunkure Post #32



Quote from Rantent
Explain destructive. Certainly energy is not destructive to life. Things tend not to survive well near absolute zero.
Energy mixes things up, which is good, so long as they aren't too shaken.
Quote from name:Cervantes
I still don't see how tagging on the "It happened for millions of years" prefix makes things seem more likely to happen; adding on years just adds on time for entropic affects to take place upon the system, the system being these chemical reactions brining forth life.

Here is an excerpt from this wiki page:
Quote from nameWikipedia
The second law of thermodynamics is an expression of the universal principle of entropy, stating that the entropy of an isolated system which is not in equilibrium will tend to increase over time...

Taking this into consideration makes for an isolated system of complex chemicals lasting for millions of years seem very unlikely; anything could disturb the process, and that process itself isn't even as of yet described or theorized in a reasonable and in-depth manner.

I'm just pointing out things to think about, I'm not just attacking things out of spite. These are just things to take into consideration before making decisions.



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Mar 14 2010, 7:03 pm Syphon Post #33



Quote from CecilSunkure
Quote from MasterJohnny
I do not think exogenesis is very possible because from what I know of astronomy. Space has extreme temperatures and radiation. Cells would be screwed in space.
Yeah I would tend to agree, but I watched this TV show one time that was about the ten toughest animals. The toughest one was this tiny bug thingy called a water bear. This little bug fed on tiny moss, and swam in water. It looked like a little plushy bear. The point is, they said on TV that this thing could survive the vacuum of space. So I don't think it's too far fetched to say that space would always kill everything in it. Just a thought.

Tardigrades look nothing like plush bears.

Quote from CecilSunkure
Quote from ProtoTank
[quote=name:ProtoTank]Laws of thermodynamics whaa? The second law of thermodynamics is about Entropy. You burn a tree down, the tree is spent, you can't put it back together. The end. It doesn't say anything about the creation of that tree. You could turn it on its head and say, "The smoke and ash will never make a tree on their own" - of course they wont! thats moving backwards, and no one is arguing that. AND if they are, then they need to reevaluate their logic.
Oh, I was referring to that because a system that isn't in equilibrium will tend towards chaos (entropy). There are quite a few versions of the second law, but my point was that without intelligent intervention, any raw energy applied over matter results in a destructive outcome (usually), and that applying energy over a vast amount of time only allows for more resulting chaos, especially if raw energy is applied to something orderly. I can only see adding in vast amounts of time allowing for new inputs of energy (events like rain, earthquakes, volcanic eruptions, storms, lighting) being a destructive force that would interrupt whatever complex combination of molecules that was occurring. Of course, this is just my opinion, and I was just trying to show you why I thought so.

Quote from ProtoTank
And also - I hate myself for proposing something like this - What are the other (logical please) options?

Considering natural laws, there really isn't any other natural explanation for the origins of life.
Yeah I'm really not sure. I've never found any sort of spontaneous generation idea or theory to be convincing, and I don't like most of the religions out there. I'm just posting in here to get people to think about their own views critically :)

There have been two states the Earth has existed in since it began to be capable of supporting life: Lifeless, with no complex chemical reactions governing anything. Simple. Lifed, with innumerable ones governing every aspect of quadrillions of animate beings in innumerable ways. Entropy has increased.

Regardless of this, the Earth is not a closed system. The second law of thermodynamics does not apply to it. It applies to the Universe.

Quote from CecilSunkure
No I do not, I get most of my information pertaining to these sorts of topics from my IB Biology class. I've never heard of that website.

As for the irreducibility of cells, I never thought anyone would want to debate that. The thing is, there are plenty of things we do not know about cells, especially pertaining to DNA replication. One example of this would be the long segments of code in the genetic material that are extremely repetitive and seem to serve no purpose, as they aren't actually translated into the RNA strands to be used in transcription. These segments, if I recall correctly, look something like AAACCAAACCAAACC and so on; very repetitive and seemingly useless. I'm sure the function of certain aspects of cells are vague or unknown, or that certain aspects of certain cells aren't necessary in certain circumstances.

I should clarify: the macro processes of cells are all necessary, in present circumstances, for cells to survive. Cells need their nucleus, they need their bi-lipid layers to have both a hydrophobic tail and hydrophylic head, they need ribsomes in order to synthesize proteins, etc. etc.

The point wasn't that cells are perfectly irreducibly complex, but that the complexity necessary to have functioning and living material is a very complex starting point.

All of the things you listed as necessary are not necessary, and there are examples of cells which lack each. The coding segments you're talking about are called telomeres. They are transcribed, and their purpose is to pad that which is an imperfect process. Each time a cell replicates or transcribes DNA, the ends of the strand undergo damage, once the damage starts to creep into the actual coding DNA, the cell approaches its Hayflick limit and can no longer divide. It dies, as do all its daughter cells. Long, repetitive, non-coding strands make it take longer for this process to occur.

Cells are most definitely not irreducibly complex.



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Mar 15 2010, 6:55 pm Kaidon Post #34



I'm not sure why the 'scholarly' community throws creationism out of the window so quickly and in such pomp that it cannot and even will not be discussed as a possibility for the origin of life.

To quote a few numbers:

Most mathematicians consider anything where the odds are 1 in 1050 to be impossible. (Borel's Law)

In order for life to form without a 'creator' (i.e. God), the traditional formula for the simplest of life forms is 1 in 1040,000.

While numbers vary, some evolutionists themselves impose harder numbers than this: Carl Sagan, Ph.D., of Cornell University--a prominent evolutionist--proposed that it is 1 in 102,000,000,000.

(http://www.scribd.com/doc/448517/Evolution-What-Are-the-Odds)

Roger Penrose, a close friend of the famous atheist Richard Dawkins, calculated it to be 1010123, a number bigger than the number generally calculated to be the total number of atoms in the universe.

(http://www.faizani.com/news/news_2003/math_impossibility.html)

As a firm believer in evolution and a world that changes dynamically, one that is older than the 6-10,000 years that Creationists propose, I believe Theistic Evolution is a viable option for the origin of life.



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Mar 15 2010, 11:19 pm ClansAreForGays Post #35



Your biased numbers are meaningless because there are 5 problems with creationist calculations:
Quote
1) They calculate the probability of the formation of a "modern" protein, or even a complete bacterium with all "modern" proteins, by random events. This is not the abiogenesis theory at all.

2) They assume that there is a fixed number of proteins, with fixed sequences for each protein, that are required for life.

3) They calculate the probability of sequential trials, rather than simultaneous trials.

4) They misunderstand what is meant by a probability calculation.

5) They seriously underestimate the number of functional enzymes/ribozymes present in a group of random sequences
source http://www.talkorigins.org/faqs/abioprob/abioprob.html

Also:


Post has been edited 1 time(s), last time on Mar 15 2010, 11:26 pm by ClansAreForGays.




Mar 16 2010, 7:09 pm grAffe Post #36



For Abiogenesis, people always use the example of monkeys randomly typing on a keyboard and are able to produce Shakespeare's plays a couple times in a row. However, actual Abiogenesis is like a similar scenario, except each time a monkey types a wrong letter, that letter is deleted, and each time the correct letter is typed, it is saved. If we apply this method, the chances don't seem that far-fetched. It's not spontaneous existence. It's a phenomenon that is inevitable with our universe's laws.



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Mar 16 2010, 7:51 pm CecilSunkure Post #37



Quote from grAffe
For Abiogenesis, people always use the example of monkeys randomly typing on a keyboard and are able to produce Shakespeare's plays a couple times in a row. However, actual Abiogenesis is like a similar scenario, except each time a monkey types a wrong letter, that letter is deleted, and each time the correct letter is typed, it is saved. If we apply this method, the chances don't seem that far-fetched. It's not spontaneous existence. It's a phenomenon that is inevitable with our universe's laws.
That isn't actually true until you have the life for natural selection to act upon. Until you have a system able to provide, or at least simulate natural selection, then that system of checks and balances doesn't exist. One cannot say that a system of checks and recordings existed and expect it to make perfect sense.



Separating a process into individual steps only makes the chances of each individual step being completed successfully. If you consider the probability of two or more process happening in concurrence, then you must multiply the probability of each process with each process, resulting in the same final probability as if a single process had occurred. This is true for any amount of processes, no matter where you think the process begins or ends, or whether or not you even think it has an ending.



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Mar 16 2010, 7:59 pm Vrael Post #38



Quote from CecilSunkure
Separating a process into individual steps only makes the chances of each individual step being completed successfully. If you consider the probability of two or more process happening in concurrence, then you must multiply the probability of each process with each process, resulting in the same final probability as if a single process had occurred. This is true for any amount of processes, no matter where you think the process begins or ends, or whether or not you even think it has an ending.
This is actually completely false. If all the events in the process were completely independant it would be true, but the probability of an event given the occurance of a second non-independant event is much different than the probability of two independant events occuring. In the case of abiogenesis, it is almost certainly the case that everything following the first event is dependant upon the first event, and hence has a much greater chance of occurance. In mathmatical terms, the probability of a conditional event E given that F has occured is P(E|F) = P(EF)/P(F). Since P(F) is much smaller than 1, it will drastically increase the probability of E occuring, if E is the next step in the abiogenesis process.



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Mar 16 2010, 9:47 pm CecilSunkure Post #39



Quote from Vrael
Quote from CecilSunkure
Separating a process into individual steps only makes the chances of each individual step being completed successfully. If you consider the probability of two or more process happening in concurrence, then you must multiply the probability of each process with each process, resulting in the same final probability as if a single process had occurred. This is true for any amount of processes, no matter where you think the process begins or ends, or whether or not you even think it has an ending.
This is actually completely false. If all the events in the process were completely independant it would be true, but the probability of an event given the occurance of a second non-independant event is much different than the probability of two independant events occuring. In the case of abiogenesis, it is almost certainly the case that everything following the first event is dependant upon the first event, and hence has a much greater chance of occurance. In mathmatical terms, the probability of a conditional event E given that F has occured is P(E|F) = P(EF)/P(F). Since P(F) is much smaller than 1, it will drastically increase the probability of E occuring, if E is the next step in the abiogenesis process.
Yes, that is true. But, that is taking the probability of only F occurring after dividing it by the probability of E occurring. If you were to calculate the probability of both occurring in sequence, not the probability of F occurring in the instance of E already occuring, wouldn't it be P(F) * P((EF)/P(F))? Or, simplified, P(E)P(F)?

So, if you start from back when no life existed, and looked at life now, the probability of life as we have it now spontaneously jumping from non-existence to existence is the same (excluding the factor of time), as if you were to split the generation into separate processes, because the probability of each individual process, given that the occurrence of each previous process was successful, multiplied upon one another results in a value equal to that of a single spontaneous generation.

If you don't ignore the factor of time, entropic action upon the system (the chemicals developing into life), have a lot of time to be disturbed, thus worsening the chance of the overall outcome. This however doesn't really apply if no entropic action is occurring, e.g. the entire planet's conditions are prime to foster these productive chemical reactions.

Post has been edited 3 time(s), last time on Mar 17 2010, 3:38 am by CecilSunkure.



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Mar 16 2010, 10:54 pm Vrael Post #40



I'm not sure exactly how these "scientists" or whoever calculates these probabilities, because this situation is obviously extremely complex.

If we take the simple chain of events depicted under "real theory of abiogenesis" we can make some simpifying assumptions. If we have a situation where there are no polymers formed, then it's obvious that the formation of replicating polymers would have to happen independantly of other events, in which case we could simply take the probability that that occurs naturally and be done with it. However, I don't think you can get to "replicating polymers" without having passed the "polymers" stage, which means the events are dependant on one another. Since they are dependant, the probability changes at each step. The further down the chain you are, the more likely each new step is going to be. Lets call these events A = polymers, B = replicating polymers, C = hypercycle, D = protobiont, E = bacteria. For bacteria to occur, you need either bacteria to spontaneously appear, or if you can build your way up this chain. That is to say, if polymers are around in nature, its much more likely we'll have replicating polymers as well. So if we have polymers, then the probability of replicating polymers is affected by the existence of the polymers, and instead of just P(B) we have the situation where we are given A exists, so P(B|A). The "|" means "given" for those who don't know. Then P(B|A) = P(AB)/P(A). So now we have replicating polymers with some probability. Then if we have B, the probability of C is affected, and we have
P(C|AB) = P(ABC)/P(AB)

I have a basketball game to coach I'll come back and finish this reasoning later.

Edit: Okay I'm back.

At this point our symbolic calclations are going to get very complicated, so it might be useful to make some assumptions. In particular, That P(AB) = P(B), P(ABC) = P(C), ect. If C is contained in B is contained in A, this is true (think of them as concentric rings). What this would mean in reality is that replicating polymers can not first happen without polymers, and if the probability of replicating polymers happening without polymers first is small enough, this assumption makes sense.
Then:
P(B|A) = P(AB)/P(A) = P(B)/P(A)
P(C|AB) = P(ABC)/P(AB) = P(C)/P(B)
P(D|ABC) = P(ABCD)/P(ABC) = P(D)/P(C)
P(E|ABCD) = P(ABCDE)/P(ABCD) = P(E)/P(D)

Then with some algebra skills, and the knowledge we want P(ABCDE)
P(ABCDE) = P(E)*P(ABCD)/P(D)
P(ABCD) = P(D)*P(ABC)/P(C)
P(ABC) = P(C)*P(AB)/P(B)
P(AB) = P(B)/P(A)

When we substitute into each expression, we end up with
P(ABCDE) = P(E)*P(D)*P(C)*P(B) / P(D)*P(C)*P(B)*P(A)

P(ABCDE) = P(E)/P(A), which is much larger than P(A)*P(B)*P(C)*P(D)*P(E)

This is the probability that the chain completes given that the first step (A) has happened and that each new step depends in the prior step. Of course, there could be assumptions that are wrong, like maybe there needs to be a critical polymer density for the next step to occur, but I'm fairly certain that the abiogenesis process does not consist of independant events in the formulation of a single bacteria.

Post has been edited 1 time(s), last time on Mar 17 2010, 2:00 am by Vrael.



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